Senolytic supplements are typically recommended to be taken for only 2 days a week (or once every couple of weeks) because the “hit and run” approach is considered most effective for senolytic supplements; meaning you administer a burst of the compound to target senescent cells, then allow a break for the body to naturally clear them out, similar to how you wouldn’t prune a plant every day, but rather periodically as needed.
Key points about this approach:
• Senescent cell accumulation is gradual:
Senescent cells build up slowly over time, so a continuous daily dose of a senolytic isn’t necessary.
• Cellular repair cycle:
By taking breaks between doses, the body has time to naturally remove targeted senescent cells, allowing for a more efficient cleansing process.
• Potential side effects:
Limiting the intake period can help mitigate potential side effects associated with senolytics, while still achieving the desired results.
Fisetin
Quercetin